Frank Lampard knocked old boss Jose Mourinho out of the EFL Cup as Derby County beat Manchester United on penalties, while Burton Albion triumphed against Burnley.
Marouane Fellaini's late equaliser took Tuesday's tie to a shootout following a 2-2 draw at Old Trafford, with Scott Carson saving Phil Jones' poor penalty to complete a dramatic 8-7 success for the Championship side.
Harry Wilson and Jack Marriott had earlier struck for the Rams as Lampard enjoyed a memorable reunion with Mourinho, his manager at Chelsea.
United's rivals Manchester City made short work of League One side Oxford United as the holders progressed to the fourth round thanks to a 3-0 win.
Phil Foden helped to create goals for Gabriel Jesus and Riyad Mahrez before scoring his first goal for the club to wrap up a star performance.
Yeeeeeeessss @PhilFoden— Fernandinho (@fernandinho) September 25, 2018
Along with United's exit, the other big shock of the day came at Burton, where Burnley's awful cup competitions record under Sean Dyche continued with a 2-1 loss.
Kevin Long's header gave the Premier League team the lead, but League One Burton hit back through Liam Boyce, who then set up Jamie Allen for a late winner.
Penalties were needed in the all-Premier League tie at Molineux, with Danny Ward saving three spot-kicks after a goalless draw to book Leicester City a fourth-round berth at the expense of Wolves.
Go on the Warden Penalty saving masterclass @dan_ward52— James Maddison (@Madders10) September 25, 2018
Callum Wilson scored a 94th-minute winner to secure a 3-2 home victory for Bournemouth against Blackburn Rovers, while Andros Townsend struck twice as Crystal Palace won 3-0 at West Brom.
Jordan Rhodes' hat-trick booked Norwich City's progression with a 4-3 thriller at Wycombe Wanderers, with 15-year-old Harvey Elliott making his Fulham debut in their 3-1 win at Millwall.
Middlesbrough scored all four of their penalties to edge through in a shootout after drawing 2-2 with Preston North End, while Blackpool are in the last 16 after a 2-0 home win against 10-man QPR.
14 de diciembre 2018
|Del Potro back on court following knee injury|
|Canelo v Fielding: Rocky ready to write his own fairytale in New York|
|Boca part company with Schelotto after Copa Libertadores loss to River|
|Canelo v Fielding: Tale of the tape|
|Juventus defender Cancelo has knee surgery|
|Canelo v Fielding: Alvarez and Rocky make weight in New York|
|Spalletti does not fear another mid-season crisis at Inter|
|Salah headlines CAF Player of the Year shortlist as Koulibaly misses out|
|Beckham Jr. out of Titans clash|
|Lipsky hits the front at Leopard Creek|
|Pederson coy over Wentz back injury|
|Liverpool ´not really likely´ to be active in January window, reveals Klopp|
|Always on the move and unpredictable - Pavard reveals surprising choice over toughest opponent|
|We need to get back to respect - Lampard alarmed by hate in football|
|Giles returns to England to replace Strauss as director|
|Hansen has no issue with Milner-Skudder Toulon switch|
|Juventus to rest Ronaldo after Torino showdown|
|Titmus strikes gold again as world records tumble in Hangzhou|
|Malinga to captain Sri Lanka in New Zealand|
|Rivaldo would like ´excellent´ Isco at Barcelona|
|United a long way from Mourinho´s vision|
|´Klopp denies an answer!´ - Liverpool boss dismisses questions about ´world-class´ Pogba|
|Returning Nowitzki ´so tired´ after making NBA history|
|Aguero and De Bruyne in contention for Manchester City v Everton|
|Simeone has no plans to cash in on Costa|
|Canelo v Fielding: Alvarez´s greatest nights|
|Fabregas: Chelsea being unfairly scapegoated over racism allegations|
|Crisis? What crisis? Klopp focuses on defensive solutions for United clash|
|Hope cannot inspire Windies as Bangladesh cruise to series win|
|Benitez picks up Premier League Manager of the Month award|
|Chavez, Marquez and Canelo - Mexico´s greatest multi-weight world champions|
|Bale set to miss Real Madrid v Rayo Vallecano|
|Robben out until January as Bayern look to avoid serious injury|
|Milan avoid UEFA ban in FFP punishments.|
|Mourinho compares Liverpool to ´an amazing house´ but insists trophies matter|
|Brisbane Roar 2 Melbourne Victory 4: Muscat´s men hit A-League summit|
|Bumrah confident second Test is ´in the balance´ after India recovery|
|Isco gesture was for a corner or foul, claims Solari|
|Harris leads Australia into ascendancy on day one|
|ATP announces candidates to host future Finals|
|Ronaldo: Juventus fans refuse to lose to Torino|
|Hero Rivers feared he had cost Chargers in KC|
|Williams would welcome Llorente back to Athletic Bilbao|
|Liverpool v Manchester United: Minding the gap|
|Milan elimination unjust, fumes Leonardo|
|Paul hails ´sick´ Harden after record-breaking display|
|Liverpool v Manchester United: Salah, Mane and Firmino v Rashford, Martial and Lukaku in Opta number|
|Canelo open to GGG trilogy as he chases place in Mexican history|
|The big Friday Premier League quiz|
|Harden posts record fourth 50-point triple-double in win over Lakers|
|Barcelona squad happy with Dembele, says Alba|
|Chargers rally past Chiefs to clinch playoff spot|
|WATCH: Chargers top Chiefs on dramatic two-point conversion in final seconds|
|Suns owner Sarver committed to keeping team in Phoenix|
|Chargers WR Allen leaves with injury after near-spectacular catch|
|Socceroos not giving up on Mooy for Asian Cup|
|Cooper says Raiders owner wanted to trade him to Cowboys|
|Pochettino jokes Levy is ´worried´ about losing him|
|Barcelona would welcome Morata – Alba|
|Toure not a priority for West Ham – Pellegrini|
|Koscielny no certainty to face Southampton, says Emery|
|We gifted the game – AC Milan boss Gattuso furious after Europa League exit|
|My season starts now, says Koscielny|
|Cipriani ´at peace´ with latest England snub|
|Laporte: Deschamps must have personal reasons for France snub|
13 de diciembre 2018
|Morata injury not too serious, claims Chelsea boss Sarri|
|Hansen to leave: All Blacks coach returning focus to World Cup defence|
|I want to fight the champion! - Joshua reiterates Wilder in April ambition|
|Gundogan glad to leave Christmas holidays behind|
|I know how it feels and it hurts - Gundogan on Sterling abuse|