Gremio and Cerro Porteno reached the Copa Libertadores round of 16, while Atletico Nacional were unable to seal their spot in the knockout stage.
Brazilian side Gremio and Paraguay's Cerro Porteno advanced from Group One with respective wins over Monagas and Defensor Sporting on the penultimate matchday.
Already assured of a last-16 berth prior to kick-off following Cerro Porteno's 1-0 win at Defensor Sporting, unbeaten Gremio claimed a last-gasp 2-1 victory over Monagas on Tuesday.
Venezuelan hosts Monagas thought they had salvaged a point in the second minute of stoppage time when Walter Kannemann turned the ball into his own net after Ramiro opened the scoring in the 69th minute.
But Gremio secured their third win in five fixtures thanks to Jailson's 97th-minute penalty in Maturin.
Gremio improved to 11 points, a point clear of Cerro Porteno, who edged Defensor Sporting via Diego Churin's goal at the death.
Nacional's quest to progress from the group stage was halted following their 1-0 loss to Ecuador's Delfin.
Group Two leaders and Colombian visitors Nacional succumbed to Luis Chicaiza's 20th-minute goal.
The result left Nacional on nine points, two points ahead of Delfin and Colo Colo, who defeated Bolivar 2-0, with one round remaining.
Bolivar are still in the race to reach the last 16 with five points from five games.
22 de mayo 2018
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|Bills release Richie Incognito from reserve/retired list|
|Gentry and Pelicans want Cousins back in New Orleans|
|MLB extends Blue Jays closer Osuna´s administrative leave|
|Lloris, Jedinak and Kjaer ask FIFA to allow Guerrero to play at World Cup|
|Wolfsburg preserve Bundesliga status after play-off win over Kiel|
|Zidane was my idol and always will be - Wijnaldum|
|Liverpool ready to fly out of the blocks in Kiev - Henderson|
|Montreal Impact 0 LA Galaxy 1: Ibrahimovic sent off for slapping opponent|
21 de mayo 2018
|Real Madrid v Liverpool: Salah, Ronaldo lead the line in combined XI|
|Bertens keeps hat-trick hopes alive in Nuremberg|
|Monfils and Mannarino fail to fly the flag in Lyon|
|Morata, Fabregas, Herrera and more in Spain´s World Cup rejects XI|
|Reina to face FIGC hearing|
|Emery set to be appointed by Arsenal - reports|
|LeBron ´appreciative´ of hometown effort to put up statue of him|
|Cazorla leaves Arsenal after injury nightmare|
|Derby´s Rowett seeks permission for Stoke talks|
|Messi physically and mentally ready for the World Cup, Sampaoli proclaims|
|Murray expected to return at Rosmalen Grass Court Championships|
|More to Madrid than just Ronaldo - Robertson|
|Wolff: Red Bull and Ferrari favourites in Monaco|
|Iniesta hailed by Xavi as ´the most talented player in the history of Spain´|
|If you Googled ´European nights´, Liverpool would be top result - Klopp|
|Icardi cut from Argentina World Cup squad|
|Test recall a ´fantastic surprise´ for Buttler|
|Klopp needs Premier League to be a Liverpool great – Johnston|
|Salah is ´definitely´ world´s best - Lovren|
|Rhinos captain Watkins ruled out for eight months|
|No clue - Klopp defiant over Can to Juventus claims|
|Younis tips Babar for Pakistan greatness|
|Germany squad numbers hint at World Cup good news for Neuer|
|WATCH: Moto3 rider makes spectacular jump over crashed rival|
|Leaving out Morata ´painful´ for Spain boss Lopetegui|
|Gustard to leave England role for Harlequins|
|Nainggolan retires from Belgium duty after World Cup snub|
|Spain striker Morata misses out on World Cup selection|
|LeBron or Kawhi could lead Lakers to the Finals - World Peace|
|Serena steps up Roland Garros training ahead of French Open|
|Nainggolan left out of Belgium´s World Cup squad|
|The long goodbye: Iniesta sits alone in Camp Nou after final Barcelona match|
|Wane to leave Warriors at end of season|
|Dr Fury will see you now - Tyson plans future career in medicine|
|Harden, D´Antoni rue ´soft´ Rockets performance in Warriors drubbing|
|Liverpool players can change their lives in Kiev, says Gerrard|
|Real Madrid v Liverpool: Can great deeds of the past fuel the bid for Champions League glory?|
|Wash your mouth out! - Curry´s expletive outburst earns scolding from mother|
|Rakitic lost for words as Iniesta heads for Barcelona exit|
|Conte: Chelsea must overhaul squad to change style|
|Johnston: Liverpool can´t lose Suarez, Coutinho and Salah!|
|Messi: I like Griezmann, he´s one of the best|
|Ohtani says he´s not good enough for Home Run Derby yet|
|Mendy: France are eyeing World Cup glory|
|Scott accepts two-week ban for Walker punch|
|Braves rally for six runs in the ninth to defeat Marlins|
|MLS Review: Red Bulls upstage Atlanta thanks to Wright-Phillips brace|
|Warriors breeze past Rockets in game three|
|We have a quality squad – Man City chairman hints at caution in transfer market|
|Wise cruises to maiden PGA Tour victory at Byron Nelson|
|Matic: United can fight for Premier League and Champions League with experience|
|Golden Knights GM on Stanley Cup Finals berth: I don´t know how we did it|
|I did a ´s*** job´ defending LeBron James – Morris|
|Dembele suffers sprained right ankle|
|We know Fellaini´s not going to renew with United – Mirabelli suggests Milan move|
|Cavs´ Lue not satisfied with just one win|
|They even whistled at Torres – Simeone backs Griezmann|
|I arrived as a boy, I leave as a man – Iniesta in emotional Barcelona farewell|
|Lingard: Wembley loss my worst feeling in football|
|Cahill: Conte uncertainty affecting Chelsea|
|Sarri has run out of time – Napoli chief De Laurentiis|