Frank Lampard knocked old boss Jose Mourinho out of the EFL Cup as Derby County beat Manchester United on penalties, while Burton Albion triumphed against Burnley.
Marouane Fellaini's late equaliser took Tuesday's tie to a shootout following a 2-2 draw at Old Trafford, with Scott Carson saving Phil Jones' poor penalty to complete a dramatic 8-7 success for the Championship side.
Harry Wilson and Jack Marriott had earlier struck for the Rams as Lampard enjoyed a memorable reunion with Mourinho, his manager at Chelsea.
United's rivals Manchester City made short work of League One side Oxford United as the holders progressed to the fourth round thanks to a 3-0 win.
Phil Foden helped to create goals for Gabriel Jesus and Riyad Mahrez before scoring his first goal for the club to wrap up a star performance.
Yeeeeeeessss @PhilFoden— Fernandinho (@fernandinho) September 25, 2018
Along with United's exit, the other big shock of the day came at Burton, where Burnley's awful cup competitions record under Sean Dyche continued with a 2-1 loss.
Kevin Long's header gave the Premier League team the lead, but League One Burton hit back through Liam Boyce, who then set up Jamie Allen for a late winner.
Penalties were needed in the all-Premier League tie at Molineux, with Danny Ward saving three spot-kicks after a goalless draw to book Leicester City a fourth-round berth at the expense of Wolves.
Go on the Warden Penalty saving masterclass @dan_ward52— James Maddison (@Madders10) September 25, 2018
Callum Wilson scored a 94th-minute winner to secure a 3-2 home victory for Bournemouth against Blackburn Rovers, while Andros Townsend struck twice as Crystal Palace won 3-0 at West Brom.
Jordan Rhodes' hat-trick booked Norwich City's progression with a 4-3 thriller at Wycombe Wanderers, with 15-year-old Harvey Elliott making his Fulham debut in their 3-1 win at Millwall.
Middlesbrough scored all four of their penalties to edge through in a shootout after drawing 2-2 with Preston North End, while Blackpool are in the last 16 after a 2-0 home win against 10-man QPR.
16 de diciembre 2018
|Thunder´s Westbrook: ´When we defend like that — best team in the league´|
|Kante at his best further forward, reiterates Sarri|
|Rose capitulates in Indonesia to squander chance to top rankings|
|Fielding: The better man won but I lived a dream|
|Rallying Bulls stun Spurs, LeBron and Ball post triple-doubles|
|Latham century puts New Zealand in commanding position|
|Mayfield leads Browns past Broncos|
|Canelo-GGG trilogy? We can make it happen – Alvarez|
|Canelo outclasses Fielding by third-round TKO|
|Farmer retains title prior to Canelo-Fielding bout|
|Qatar unveils Lusail Stadium for 2022 World Cup|
|Lakers pair LeBron, Ball revel in triple-double feat|
|Allegri hails ´great professional´ Ronaldo|
|LeBron, Ball first Lakers team-mates with triple-doubles in same game since 1982|
|Premier League contenders Liverpool ready to win titles – Henderson|
|Hopkins´ two TDs help Texans close in on AFC South title with win over Jets|
|Courtois: Simeone criticises Real Madrid to boost popularity|
|Mourinho in the dark over transfers as Pogba rumours swirl again|
|Mourinho marvels at Salah going nuclear|
|The lucky ones - Mourinho assesses Liverpool´s title charge|
15 de diciembre 2018
|Juventus boss Allegri turned his back on Ronaldo penalty|
|Dickerson hoping Barkley falls short of breaking his records|
|Bristol shock La Rochelle, Clermont win again|
|LeBron: Meeting Jordan for first time was godly|
|Ronaldo scores Juventus´ 5,000th Serie A goal|
|I was all over the place - Allen reaches Scottish Open final despite hangovers|
|Solari defends wasteful Asensio after slim Madrid win|
|Torino 0 Juventus 1: Ronaldo capitalises on Zaza woe|
|I do my work on the pitch – Icardi unconcerned by Inter contract discussions|
|Lyon defender Rafael set for three months out|
|Inter captain Icardi is the ´perfect´ striker – Spalletti|
|Fulham have to stick together, says Ranieri|
|Nuno hails ´very special´ Wolves achievement after third straight win|
|Stuttgart captain Gentner´s father dies at Hertha fixture|
|Valverde not desperate for new centre-back amid talk of Christensen loan|
|Toulouse and Saracens stay perfect in Champions Cup|
|Kovac lauds Bayern´s best performance of the season|
|Barcelona can get the best out of Coutinho and Dembele, claims Valverde|
|Borussia Dortmund 2 Werder Bremen 1: Alcacer and Reus guarantee top spot for mid-season break|
|Bristol City 2 Norwich City 2: Canaries knocked off their perch despite late equaliser|
|Atletico´s fighting spirit lauded by Simeone, Godin|
|Hodgson relieved to see Palace end Zaha curse|
|Real Madrid 1 Rayo Vallecano 0: Benzema secures steady response to CSKA loss|
|Fulham 0 West Ham 2: Snodgrass, Antonio punish profligate hosts|
|Warnock brands refereeing situation ´a disgrace´ after Watford defeat|
|Inter 1 Udinese 0: Icardi penalty gets lethargic Nerazzurri back on track|
|Wagner retains belief in survival bid despite Newcastle defeat|
|Griezmann feeling the strain after busy 2018|
|Pochettino ´so pleased´ as tired Tottenham scrap to Burnley win|
|Man Utd hand Smalling new contract|
|ES Tunis 0 Al Ain 3: Convincing victory books River Plate semi|
|Championship Review: Bamford fires Leeds to summit, Middlesbrough defeated by QPR|
|Curry reacts to Kings´ trolling with moon landing video|
|Wentz ruled out of Rams clash|
|Pochettino reaches 100 Premier League wins for Tottenham faster than Wenger for Arsenal|
|Real Valladolid 2 Atletico Madrid 3: Griezmann the hero on landmark appearance|
|Silva rues Richarlison´s missed chances at City|
|Gibson has no worries over Proteas batsmen|
|Wolves 2 Bournemouth 0: Jimenez and Cavaleiro score against toothless Cherries|
|Crystal Palace 1 Leicester City 0: Captain Milivojevic earns vital victory|
|Watford 3 Cardiff City 2: Hornets hang on despite late fightback|
|Tottenham 1 Burnley 0: Eriksen snatches victory at the death|
|Huddersfield Town 0 Newcastle United 1: Rondon strike settles scrap|
|Sabres suspend forward Berglund for failing to report to the team|
|Saunders thanks Fury for getting him ´back on the right track´|
|Hannover 0 Bayern Munich 4: Gnabry and Kimmich star in crushing win|
|I admire Sterling – Guardiola|
|City´s strength in depth makes it hard for me – Jesus|
|Jamieson holds slender lead in Malelane|
|Kashima Antlers 3 Guadalajara 2: Comeback win sets up Real Madrid semi-final|