Andy Murray and Stan Wawrinka were bundled out of the Monte-Carlo Masters on Thursday, but Novak Djokovic and Rafael Nadal reached the quarter-finals in contrasting fashion.
Albert Ramos-Vinolas fought back from 4-0 down in the final set to claim the scalp of top seed Murray, who went down 2-6 6-2 7-5 on the clay in the principality.
The world number one was not the only big name to bow out, as US Open champion Wawrinka was beaten 6-4 6-4 by Pablo Cuevas.
Twelve-time grand slam champion Djokovic showed he still has work to do in order to return to the peak of his powers, but saw off Pablo Carreno Busta 6-2 4-6 6-4.
Fourth seed and defending champion Nadal only needed 68 minutes to beat birthday boy Alexander Zverev 6-1 6-1.
MURRAY RUES 'BAD DECISIONS'
Murray looked bound for the last eight when he won the first four games of the deciding set, but the three-time grand slam champion was left stunned by a defiant Ramos-Vinolas.
The top seed grew increasingly disgruntled in the final set as Spaniard Ramos-Vinolas turned the tide to seal the biggest victory of his career and book a last-eight meeting with Marin Cilic.
Wimbledon champion Murray said: "A few times, I made some bad decisions. That's something that, with my team, I'll look at, watch some parts of the match over, see the shots that I chose and what I would do differently."
WOE FOR WAWRINKA
Cuevas had never beaten a top-four player before stepping out on court against Wawrinka, but needed just the two sets to put that record right.
The 16th seed from Uruguay did not face a solitary break point against the three-time grand slam champion in the first meeting between the two.
DJOKOVIC PASSES CARRENO BUSTA TEST
Djokovic was in danger of following Murray and Wawrinka out of the tournament, but hung in there to get past a defiant Carreno Busta and seal a clash with David Goffin.
It looked set to be plain sailing for the world number two when he won six games in a row to lead 2-0 in the second set, but the Spaniard was not finished yet.
Djokovic lost the next five games before Carreno Busta took it into a decider and the underdog had the Serb in trouble at 15-40 and 4-4 in the final set, but was unable to pull off a shock.
NADAL SPOILS THE PARTY
Nine-time Monte Carlo champion Nadal did not come bearing gifts on Zverev's 20th birthday, racing to victory in a one-sided contest.
The Spanish great broke five times as he won at a canter and will now face Diego Schwartzman, who reaches his first Masters quarter-final with a 6-3 6-0 demolition of Jan-Lennard Struff.
Lucas Pouille will take on Cuevas after the Frenchman was given an easy passage into the last eight, with compatriot Adrian Mannarino retiring due to a hip injury early in the first set.
27 de julio 2017
|Philadelphia Union 3 Columbus Crew 0: Sapong leads hosts to win|
|Roberts signs long-term Broncos deal|
|Wallabies captain Moore set to retire from international rugby|
|Barcelona 1 Manchester United 0: PSG target Neymar inspires ICC win|
|Isner eases into last eight in Atlanta|
|Marotta: Juventus have made Keita offer, open to Matuidi|
|Conte: I would pick Kane if I had to sign a striker|
|Jets pick up Whitehead after tumultuous week|
|Mourinho hints Ibrahimovic could make Man United return|
|Wizards sign Wall to lucrative four-year extension|
|Patrick Kluivert´s nine-year-old son signs Nike deal|
|Fassone: Bayern´s Sanches too expensive for Milan|
|Johnson´s back finally feeling good after Masters fall|
26 de julio 2017
|Champions League Review: Van de Beek earns Ajax away goal in Nice tie|
|Hurt Sharapova vows to bounce back|
|Locked dorm forces Martellus Bennett to sleep in Packers locker room|
|Celtic 0 Rosenborg 0: Unconvincing hosts fortunate to escape with draw|
|Keeping players against their will is counterproductive - Marotta explains Bonucci exit|
|Goffin survives second-round scare in Gstaad|
|Peaty vows to go even quicker after record-breaking World Championships|
|Du Plessis delivers warning to England debutant Westley|
|Serie A fixtures: Potential for AC Milan nightmare October as Bonucci faces pre-Halloween Juve reuni|
|Serie A fixtures: Juventus to face gruelling run-in|
|Serie A fixtures: Inter meet AC Milan in October, Derby d´Italia set for December|
|Minnesota Vikings sign Everson Griffen to massive extension|
|Mourinho: I had to beg Real Madrid to let me go|
|Chelsea captain Cahill: Terry will be first person I call|
|Fury appears to call time on boxing career|
|Browns´ Garrett ´ready to go´ after foot injury|
|Serie A fixtures: Juventus face Cagliari in opening round|
|Pakistan captain Sarfraz signs short-term Yorkshire deal|
|Peaty storms to gold as Ledecky suffers surprise loss|
|Sarr chooses Rennes over Barcelona|
|Terim leaves Turkey role after brawl|
|Gunaratne to miss rest of India series with fractured thumb|
|Marquez offers support to Nieto after Ibiza accident|
|Sevastova and Garcia sail through in Bastad, Nanchang woe for Zhang|
|Citroen turn to Loeb to revive their fortunes|
|Big Four-ever? Djokovic can return to emulate evergreen Federer and resurgent Nadal|
|Relaxed Schippers ready for World Championships|
|Bacca left out of Milan squad amid Marseille rumours|
|Zlatan Ibrahimovic bang on the money in latest Instagram post|
|Roland-Jones has been banging on the England door - Root|
|Barkley will 100 per cent leave Everton - Koeman|
|City can challenge Madrid – Sane|
|Fabinho and Lemar staying at Monaco - Vasilyev|
|Dhawan and Pujara make Sri Lanka suffer|
|Mbappe in talks over new Monaco deal|
|Djokovic to miss remainder of 2017|
|Toure urges Mendy to adapt quickly|
|Roland-Jones to replace injured Wood for Oval Test|
|Hasler dismisses talk of Bulldogs showdown talks|
|Wigan and Hull FC to play historic Super League clash in Australia|
|Inter can forget about Vidal - Ancelotti|
|Hamilton and Raikkonen in hunt for Hungaroring records – Hungarian GP in numbers|
|Perisic to Man Utd dependent on Inter finding valid alternative - Spalletti|
|Costly Dhawan drop leaves Gunaratne with fractured thumb|
|Guardiola refuses to rule out City rivalling Madrid in Mbappe pursuit|
|Recovering Slater expects to face Cowboys|
|Bayern Munich as big if not bigger than Real Madrid - James Rodriguez|
|All Blacks vice-captain Smith to take sabbatical|
|Real Madrid friends reunited: Zinedine Zidane, Raul and David Beckham meet in LA|
|Lure of Pep made it easy for Danilo to choose Man City over Chelsea|
|Shaw, Brewers won´t back down in tight NL Central race|
|Man Utd boss Mourinho says ´dangerous´ fees a threat to football|
|Victory star Rojas set to return to Europe|
|Lynn to miss up to seven months after shoulder surgery|
|Beckham happy for Madrid coach Zidane|
|Mayweather-McGregor to be shown in U.S. movie theatres|
|Toluca 0 Atletico Madrid 0: LaLiga giants held to dour draw|